Question: Blood glucose is usually about 3 – 5 mM except after a meal when
it usually rises. A pancreatic b…
Blood glucose is usually about 3 – 5 mM except after a meal when
it usually rises. A pancreatic beta-islet cell usually only
secretes insulin into the blood after a meal. Which of the
following observations best explains how a beta-islet cell senses
that a meal has been eaten?
A. The trans-membrane voltage potential of the beta-islet plasma
membrane increases dramatically and Ca++ is released.
B. The G-proteins of the glucose receptor on the plasma membrane
are activated and a signaling cascade causes insulin to be
C. The Km of GLUT 2 for glucose is 17 mM.
D. Hexokinase is inhibited
E. Glucose 6-phosphate dehydrogenase is activated and glycolysis