Question: A carbohydrate overload model was used in 8 horses to evaluate
Starling forces and hemodynamics o…
A carbohydrate overload model was used in 8 horses to evaluate
Starling forces and hemodynamics of the digit during the prodromal
stage of acute laminitis.A pump-perfused extracorporeal digital
preparation was used to evaluate blood flow, arterial pressure,
venous pressure, capillary pressure, isogravimetric capillary
filtration coefficient, osmotic reflection coefficient, and
vascular compliance. From these data, pre- and postcapillary
resistances and pre- to postcapillary resistance ratios were
determined. Vascular and tissue oncotic pressures were estimated
from plasma and lymph protein concentrations, respectively. The
osmotic reflection coefficient, an estimation of capillary
permeability, was determined by means of the lymph protein
wash-down technique. Using the collected data, tissue pressure in
the digit was calculated by use of the Starling equation.
In the isolated digit, mean isogravimetric capillary pressure
was 55.13 mm of Hg.
Mean plasma and lymph oncotic pressures were 22.29 mm of Hg and
7.2 mm of Hg.
The mean osmotic reflection coefficient was 0.66.
The mean capillary filtration coefficient was 0.003 ml/min/mm of
Hg/100 g, and mean interstitial fluid pressure was 44.82 mm of
The high capillary pressure appeared to be caused by high
vascular resistance from the venous side, predisposing to enhanced
capillary filtration and interstitial fluid accumulation.”
What is the lymph production rate in these horses?