Question: 2. Methionine is an essential amino acid for mammals, but its biosynthetic pathway in bacteria is…


2. Methionine is an essential amino acid for mammals, but its biosynthetic pathway in bacteria is shown below. The step in the pathway affected by each of six bacterial different mutations, metA-F, is indicated by a double-arrow (>> metF metD metA metB metC metE AspartateララAspartateララHomoserineララo--succinylー ううCystathionineララHomocysteineララMethionine semialdehyde A. Using the above biosynthetic pathway for methionine, predict the growth () or failure to grow (-) of the met mutants when placed on a medium supplemented with each of the following compounds. Mutants metA metB metc metD metE metF metH Supplement None Aspartate Aspartate semialde Homoserine o---succinylhomoserine tathionine Но eine Methionine (Graded as right minus wrong) B. Another methionine mutant was isolated and designated metH. The growth pattern of this mutant is shown in the table above. Using the growth pattern, determine the step in the pathway that is blocked in metH

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2. Methionine is an essential amino acid for mammals, but its biosynthetic pathway in bacteria is shown below. The step in the pathway affected by each of six bacterial different mutations, metA-F, is indicated by a double-arrow (>> metF metD metA metB metC metE AspartateララAspartateララHomoserineララo–succinylー ううCystathionineララHomocysteineララMethionine semialdehyde A. Using the above biosynthetic pathway for methionine, predict the growth () or failure to grow (-) of the met mutants when placed on a medium supplemented with each of the following compounds. Mutants metA metB metc metD metE metF metH Supplement None Aspartate Aspartate semialde Homoserine o—succinylhomoserine tathionine Но eine Methionine (Graded as right minus wrong) B. Another methionine mutant was isolated and designated metH. The growth pattern of this mutant is shown in the table above. Using the growth pattern, determine the step in the pathway that is blocked in metH

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