Question: 16. All of the following ements about cellular trafficking are true e a) COPII-coated vesicles mo…


16. All of the following ements about cellular trafficking are true e a) COPII-coated vesicles move materials from ER to Gol 까COPI-coated vesicles move materials from the Golgi apparatus to secretory vesicles. c) clatherin-coated vesicles deliver cargo from the Golgi apparatus to their final destinations. d) v-SNAREs occur in vesicles; t-SNAREs occur on target sites e) tethering or accessory proteins mediate docking between target membranes and vesicle membranes 17. Which of the following is a function associated with the smooth endoplasmic reticulum in at least some a) synthesis of steroid hormones b) detoxification of many organic compounds, like barbiturates and ethanol c) release of glucose into the bloodstream d) sequestration of calcium Ca2 ions within the cisternal space All of these are correct 8. What appears to be the purpose of molecular chaperones like BiP? ognize and bind to unfolded or misfolded proteins and help them attain their native structure They recognize and bind to unfolded or misfolded DNAs and help them attain their native structure c) They recognize and bind to unfolded or misfolded RNAs and help them attain their native structure. d) They recognize and bind unfolded or misfolded carbohydrates and help them lose their native shape. e) They transport secretory proteins into secretory vesicles. 19. All of the following are characteristic of people who suffer from Tay Sachs disease EXCEPT a) They lack the lysosomal enzyme that degrades ganglioside Gut b) It is common in people of a specific Jewish ance b) mental disorder is a common e) They lack one of the proteins needed to transport cholesterol out of lysos d) it is a lysosomal storage disorder 20. How are integral membrane proteins thought to enter the lipid bilayer? a) They insert into the membrane from the RER lumen after their synthesis is comp b) The aqueous translocon channel seems to have a gate that continuously opens and closes, giving each nase (new) polypeptide segment a chance to partition itself into the lipid bilayers hydrophobic core. c) They insert into the membrane from the cytosol after their synthesis is comp d) It is thought that they burrow into the lipid bilayer. e) It is thought that they are enzymatically implanted in the lipid bilayer 21. Which of the following are proposed functions of autophagy! a) It plays a role in organelle turnover. b) It is used to cannibalize organelles when a cell is deprived of nutrients. c) It protects organisms against intracellular threats like abnormal protein aggregates and invading bacteria d) It plays a role in the regulated destruction of the cells own organelles and their replacement. All of the other answers are correct. 22. Familial hypercholesterolemia is characterized by which of the following? a defective LDL receptors on the cell membranes. b) poor attachment of the cholesterol to the extracellular matrix of cells. c) a poorly formed lipid bilayer that cannot incorporate cholesterol into cell membranes d) inhibition of the cholesterol active transport system in red blood cells. e) a general lack of glycolipids in the blood cell membranes. e) OH 23. Cystic fibrosis is the result of a malfunction of the cell in transporting which of the following ions? d) glucose b) a) Cl

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16. All of the following ements about cellular trafficking are true e a) COPII-coated vesicles move materials from ER to Gol 까COPI-coated vesicles move materials from the Golgi apparatus to secretory vesicles. c) clatherin-coated vesicles deliver cargo from the Golgi apparatus to their final destinations. d) v-SNAREs occur in vesicles; t-SNAREs occur on target sites e) tethering or accessory proteins mediate docking between target membranes and vesicle membranes 17. Which of the following is a function associated with the smooth endoplasmic reticulum in at least some a) synthesis of steroid hormones b) detoxification of many organic compounds, like barbiturates and ethanol c) release of glucose into the bloodstream d) sequestration of calcium Ca2 ions within the cisternal space All of these are correct 8. What appears to be the purpose of molecular chaperones like BiP? ognize and bind to unfolded or misfolded proteins and help them attain their native structure They recognize and bind to unfolded or misfolded DNAs and help them attain their native structure c) They recognize and bind to unfolded or misfolded RNAs and help them attain their native structure. d) They recognize and bind unfolded or misfolded carbohydrates and help them lose their native shape. e) They transport secretory proteins into secretory vesicles. 19. All of the following are characteristic of people who suffer from Tay Sachs disease EXCEPT a) They lack the lysosomal enzyme that degrades ganglioside Gut b) It is common in people of a specific Jewish ance b) mental disorder is a common e) They lack one of the proteins needed to transport cholesterol out of lysos d) it is a lysosomal storage disorder 20. How are integral membrane proteins thought to enter the lipid bilayer? a) They insert into the membrane from the RER lumen after their synthesis is comp b) The aqueous translocon channel seems to have a gate that continuously opens and closes, giving each nase (new) polypeptide segment a chance to partition itself into the lipid bilayer's hydrophobic core. c) They insert into the membrane from the cytosol after their synthesis is comp d) It is thought that they burrow into the lipid bilayer. e) It is thought that they are enzymatically implanted in the lipid bilayer 21. Which of the following are proposed functions of autophagy! a) It plays a role in organelle turnover. b) It is used to cannibalize organelles when a cell is deprived of nutrients. c) It protects organisms against intracellular threats like abnormal protein aggregates and invading bacteria d) It plays a role in the regulated destruction of the cell's own organelles and their replacement. All of the other answers are correct. 22. Familial hypercholesterolemia is characterized by which of the following? a defective LDL receptors on the cell membranes. b) poor attachment of the cholesterol to the extracellular matrix of cells. c) a poorly formed lipid bilayer that cannot incorporate cholesterol into cell membranes d) inhibition of the cholesterol active transport system in red blood cells. e) a general lack of glycolipids in the blood cell membranes. e) OH 23. Cystic fibrosis is the result of a malfunction of the cell in transporting which of the following ions? d) glucose b) a) Cl

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