Question: 0 points Sav Which of the following is false? o a.In normoxic cells, HIF-1 is not expressed and p…


0 points Sav Which of the following is false? o a.In normoxic cells, HIF-1 is not expressed and pVHL is rapidly degraded proline hydroxylase o b. When a chemically transformed cell and a normal cell are fused, the tybrid cell i initialy no longer tumorigenic O c In cancer, epigenetic changes include genome-wide hypomethylation and localized hypermethylation. o d. The Knudson hypothesis offers an explanation tor the relationship between hereditary and non-hereditary (familial and sporadic) cancers. e. The APC gene, which was identified through analysis of large families predisposed to colon cancer (Familial Adenomatous Polyposis; FAP), is also inactivated in most sporadic colon carcinomas

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0 points Sav Which of the following is false? o a.In normoxic cells, HIF-1 is not expressed and pVHL is rapidly degraded proline hydroxylase o b. When a chemically transformed cell and a normal cell are fused, the tybrid cell i initialy no longer tumorigenic O c In cancer, epigenetic changes include genome-wide hypomethylation and localized hypermethylation. o d. The Knudson hypothesis offers an explanation tor the relationship between hereditary and non-hereditary (familial and sporadic) cancers. e. The APC gene, which was identified through analysis of large families predisposed to colon cancer (Familial Adenomatous Polyposis; FAP), is also inactivated in most sporadic colon carcinomas

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